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Pancreatitis Pancreatitis, inflammation of the pancreas, represents a serious potential risk with cagrilintide as it does with other incretin-based therapies

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BMPs regulate NSC differentiation into astrocytes by acting through the phosphorylation of Smad proteins 1, 5, and 8, which combine with Smad4 in order to form a complex that translocates to the nucleus and regulates gene transcription (Itoh et al., 2000